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ULMO
Caplet
COMPOSITION :
Each caplet contains 20 mg and 40 mg Famotidine.

ACTIONS :
Famotidine is a histamine H2-antagonist receptor of the thiazole family. It inhibits basal and nocturnal gastric acid secretion
through competitive inhibition  against histamine H2-receptor on the parietal cells.
Famotidine also inhibits gastric acid secretion stimulated by food and pentagastrin. After oral administration, peak plasma
level occurs within 1-3 hours, with duration of action lasting  for 10-12 hours.

INDICATIONS :
Short-term treatment and maintenance  therapy for active duodenal ulcer.
Treatment of pathological hypersecretory conditions, eg Zollinger-Ellison syndrome and multiple endocrine adenomas.

DOSAGE AND ADMINISTRATION :
Treatment of Ulcer:
Acute : One 40 mg caplet once daily before bedtime or 0ne 20 mg caplet, twice daily, for 4 weeks. Longer treatment of
> 6-8 weeks is rarely required.
As Maintenance Therapy :
One 20 mg caplet once daily before  bedtime.
Hypersecretory Conditions :
One 20 mg caplet  every 6 hours. Dosage can be increased to individual requirement.

CONTRAINDICATION :
Patients hypersensitive to famotidine.


PRECAUTION :
Caution should be taken when given to patients with liver dysfunction. Reduce dosage in patients with renal impairment.
Exclude gastric maglinancy before treatment with famotidine.
Use in pregnancy : Safe use and lactation has not been established.
Use in children : Safe use and efficacy in children have not established.

SIDE EFFECTS :
Sometimes fever, swollen eyelid due to allergic reaction, bleeding or bruises, increased heart rate and fatigue. Headache ,
dizziness, constipation, diarrhea, thrombocytopenia and arthralgia have been also reported.

INTERACTIONS :
Concurrent administration of famotidine with drugs metabolised through microsomal liver enzyme, eg cytochrome P-450 (eg
theophylline, warfarin, diazepam) does not significantly interfere with the metabolism of those drugs.

PACKING :
Ulmo-20 caplet. Box 0f 3x10’s. Reg. No.DKL9421007304A1.
Ulmo-40 caplet. Box of 3x10’s. Reg. No.DKL9421007304B1

On medical prescription only.



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High Standard
Pyridam is Certified in  Good
Manufacturing Practices
(GMP).

Our Products have met the
International Level and
Requirement.

How to contact us
for more information

email: info@pyridam.com
Phone: +62-21-536-90112
Fax     : +62-21-532-9049